Linda Anette Kornstad Nygård

• Nygård, Linda Anette Kornstad; Mundal, Ingunn Pernille; Dahl, Lisbeth; Saltyte Benth, Jurate & Rokstad, Anne Marie Mork (2021). Limited benefit of marine protein hydrolysate on physical function and strength in older adults : a randomized controlled trial. Marine Drugs.  ISSN 1660-3397.  19(2), s 1- 14 . doi: 10.3390/md19020062 Fulltekst i vitenarkiv. Vis sammendrag

  Age-related muscle wasting can compromise functional abilities of the elderly. Protein intake stimulates muscle protein synthesis; however, ageing muscle is more resistant to stimuli. This double-blinded, randomized, controlled trial is one of the first registered studies to evaluate the effects of a supplement of marine protein hydrolysate (MPH) on measures of physical function and strength. Eighty-six older adults received nutritional supplements containing 3 g of MPH or a placebo for up to 12 months. Short Physical Performance Battery (SPPB), grip strength and gait speed were measured, and dietary intake was registered at baseline, 6 months, and 12 months. No difference was found between the intervention and control groups in mean change in SPPB (independent sample t-test, p = 0.41) or regarding time trend in SPPB, grip strength, or gait speed (linear mixed model). The participants in our study were well functioning, causing a ceiling effect in SPPB. Further, they had sufficient protein intake and were physically active. Differences in physical function between those completing the intervention and the dropouts might also have created bias in the results. We recommend that future studies of MPH be carried out on a more frail or malnourished population. Keywords: hydrolysate, fish protein, ageing, physical function, dietary assessment, seafood intake, healthy ageing

• Nygård, Linda Anette Kornstad; Dahl, Lisbeth; Mundal, Ingunn Pernille; Saltyte Benth, Jurate & Rokstad, Anne Marie Mork (2020). Protein intake, protein mealtime distribution and seafood consumption in elderly Norwegians : associations with physical function and strength. Geriatrics (Basel).  ISSN 2308-3417.  5(4), s 1- 14 . doi: 10.3390/geriatrics5040100 Fulltekst i vitenarkiv. Vis sammendrag

  Protein intake is considered important in the maintenance of muscle health in ageing. However, both the source and mealtime distribution of protein might affect the intake of protein and its effect on muscle protein synthesis. In this study, protein intake, mealtime distribution of protein, and seafood consumption were assessed in 92 older adults (aged 65+), and associations with physical performance (Short Physical Performance Battery (SPPB)), grip strength and gait speed were assessed in a multiple linear regression analysis. The participants had a mean age of 73 ± 8.9 years. Mean protein intake was 1.1 g/kg body weight. Protein intake was well distributed, with coefficient of variance between meals (CV meals) 0.6 ± 0.3. However, dinner had the highest protein intake. No associations were found between the nutrition factors and physical performance or strength; however, this result might have been caused by a ceiling effect in the chosen test batteries, as the mean score on SPPB was 10.3 ± 2.7, and 48.9% of the participants reached the top score of 12 points. Mean grip strength was 44.4 ± 9.4 kg (men) and 26.2 ± 6.8 kg (women). Mean gait speed was 1.0 ± 0.3 m/s. The interaction analysis suggests that there might be gender differences in the effect of seafood consumption on gait speed. Keywords: nutrition, protein, fish, older adults, physical performance, hand grip strength, sarcopenia, frailty

• Nygård, Linda Anette Kornstad; Mundal, Ingunn Pernille; Dahl, Lisbeth; Saltyte Benth, Jurate & Rokstad, Anne Marie Mork (2018). Nutrition and physical performance in older people—effects of marine protein hydrolysates to prevent decline in physical performance : a randomised controlled trial protocol. BMJ Open.  ISSN 2044-6055.  8(10), s 1- 7 . doi: 10.1136/bmjopen-2018-023845 Fulltekst i vitenarkiv. Vis sammendrag

  Introduction: Age-related loss of muscle mass, muscle strength and muscle function (sarcopenia) leads to a decline in physical performance, loss of independence and reduced quality of life. Nutritional supplements may delay the progression of sarcopenia. The aim of this randomised, double-blinded controlled trial including 100 participants (≥65 years) is to assess the effect of a marine protein hydrolysate (MPH) on sarcopenia-related outcomes like hand grip strength, physical performance or gait speed and to study the associations between physical performance and nutritional intake and status. Method and analysis: The intervention group (n=50) will receive 3 g of MPH per day in 12 months. The control group (n=50) receive placebo. Assessments of Short Physical Performance Battery (SPPB), hand grip strength, anthropometric measurements, nutritional status as measured by the Mini Nutritional Assessment, dietary intake, supplement use, biomarkers of protein nutrition and vitamin D, and health-related quality of life (EQ-5D), will be performed at baseline and after 6 and 12 months of intervention. Linear mixed models will be estimated to assess the effect of MPH on SPPB, hand grip strength and quality of life, as well as associations between physical performance and nutrition. Ethics and dissemination: The study has been approved by the Regional Committee in Ethics in Medical Research in Mid-Norway in September 2016 with the registration ID 2016/1152. The results will be actively disseminated through peer-reviewed journals, conference presentations, social media, broadcast media and print media.

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• Nygård, Linda Anette Kornstad (2021). Protein intake in an elderly population : is there a need for increased intake or supplementation. Ph.d.-avhandlinger i helse- og sosialfag. 2021:3.
• Måløy, Elfrid; Nygård, Linda Anette Kornstad & Eines, Trude Fløystad (2017). Få bukt med feilmedisinering. Tidsskriftet sykepleien.  ISSN 0806-7511.  105(6), s 42- 43 . doi: 10.4220/Sykepleiens.2017.62296 Vis sammendrag

  Til tross for gode tiltak og systemer for legemiddelhåndtering får mange pasienter fremdeles for mye eller feil medisin.

• Nygård, Linda Anette Kornstad (2017). Matombringing eller matomsorg?. Norsk Tidsskrift for Ernæring.  ISSN 1503-5034.  (1), s 44- 46
• Måløy, Elfrid; Nygård, Linda Anette Kornstad & Eines, Trude Fløystad (2016). Hva gjør vi med feilmedisinering?. Panorama : nettavis for Høgskolen i Molde.
• Måløy, Elfrid; Nygård, Linda Anette Kornstad & Eines, Trude Fløystad (2016). Hva gjør vi med feilmedisinering?. Tidens Krav.
• Måløy, Elfrid; Nygård, Linda Anette Kornstad & Eines, Trude Fløystad (2016). Hva gjør vi med feilmedisinering?. Romsdals Budstikke..  ISSN 0806-5160.
• Nygård, Linda Anette Kornstad (2016). Eldre, astronauter og fiskeprotein . Romsdals Budstikke..  ISSN 0806-5160.
• Dale, Karl Yngvar; Driller, Bardo; Jørgensen, Else; Nygård, Linda Anette Kornstad & Strømskag, Kjell Erik (2013). Integrasjon av praksis, undervisning og forskning : hvordan kan man sikre høyest mulig kvalitet innen omsorg og behandling av alvorlig syke og døende på kommunalt nivå?. Arbeidsnotat (Høgskolen i Molde). 2013:8. Vis sammendrag

  Det sentrale spørsmålet vi stiller er: Hvordan kan praksis, undervisning og forskning samarbeide for å legge til rette for ”best practice” innen det palliative feltet. “Best practice” er beskrevet gjennom nasjonale retningslinjer og faglige ”gullstandarder”. Her vil vi fremholde at mye avhenger dels av et godt tilrettelagt utdanningssystem, dels et godt faglig samarbeid mellom helseforetak, det kommunale praksisfeltet og utdanningsinstitusjon, og sist men ikke minst: At alle disse instanser kan inngå i et tett og gjensidig utviklende forskningssamarbeid. Vi vil argumentere for at dette gir den beste muligheten for å sikre høyest mulig kvalitet i det palliative feltet, herunder at man evner å etablere en forskningsbasert praksis som også er i tråd med nasjonale retningslinjer. I artikkelen belyses dette gjennom et case.

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